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MRPS12 Antikörper (AA 28-59)

MRPS12 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB17455 unconjugated
Produktnummer ABIN656569
  • Target Alle MRPS12 Antikörper anzeigen
    MRPS12 (Mitochondrial Ribosomal Protein S12 (MRPS12))
    Bindungsspezifität
    • 8
    • 7
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 28-59
    Reaktivität
    • 32
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 31
    • 1
    Kaninchen
    Klonalität
    • 32
    Polyklonal
    Konjugat
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MRPS12 Antikörper ist unkonjugiert
    Applikation
    • 25
    • 18
    • 15
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This MRPS12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-59 amino acids from the Central region of human MRPS12.
    Klon
    RB17455
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product MRPS12 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    MRPS12 Antibody (Center K43) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Haltbarkeit
    6 months
  • Target
    MRPS12 (Mitochondrial Ribosomal Protein S12 (MRPS12))
    Andere Bezeichnung
    MRPS12 (MRPS12 Produkte)
    Synonyme
    MPR-S12 antikoerper, MT-RPS12 antikoerper, RPMS12 antikoerper, RPS12 antikoerper, RPSM12 antikoerper, AI327385 antikoerper, Rpms12 antikoerper, rps12 antikoerper, CG7925 antikoerper, Dmel\\CG7925 antikoerper, EG:BACH59J11.1 antikoerper, MRP-S12 antikoerper, MRPS12 antikoerper, S12 antikoerper, Tko antikoerper, l(1)3Ab antikoerper, l(1)tko antikoerper, mRpS12 antikoerper, mt-rps12 antikoerper, MGC64304 antikoerper, GB10531 antikoerper, mitochondrial ribosomal protein S12 antikoerper, technical knockout antikoerper, mitochondrial ribosomal protein S12 L homeolog antikoerper, 40S ribosomal protein S12, mitochondrial antikoerper, putative mitochondrial 37S ribosomal protein MRPS12 antikoerper, fragile site, aphidicolin type, common, fra(6)(p22.2) antikoerper, MRPS12 antikoerper, Mrps12 antikoerper, tko antikoerper, mrps12.L antikoerper, LOC409723 antikoerper, mRpS12 antikoerper, mrps12 antikoerper, CAALFM_C106070WA antikoerper, mrpS12 antikoerper, FRA6C antikoerper
    Hintergrund
    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S12P family. The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics. The gene for mitochondrial seryl-tRNA synthetase is located upstream and adjacent to this gene, and both genes are possible candidates for the autosomal dominant deafness gene (DFNA4). Splice variants that differ in the 5' UTR have been found for this gene, all three variants encode the same protein.
    Molekulargewicht
    15173
    Gen-ID
    6183
    NCBI Accession
    NP_066930, NP_203526, NP_203527
    UniProt
    O15235
    Pathways
    Sensory Perception of Sound
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