IREB2 Antikörper (AA 201-230)
-
- Target Alle IREB2 Antikörper anzeigen
- IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))
-
Bindungsspezifität
- AA 201-230
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser IREB2 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
- Homologie
- M, Pig, Rat
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This IREB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 201-230 amino acids from the Central region of human IREB2.
- Klon
- RB30212
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product IREB2 Primärantikörper
-
-
- Applikationshinweise
- WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- IREB2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- Haltbarkeit
- 6 months
-
- Target
- IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))
- Andere Bezeichnung
- IREB2 (IREB2 Produkte)
- Hintergrund
- IREB2 is a RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
- Molekulargewicht
- 105059
- Gen-ID
- 3658
- NCBI Accession
- NP_004127
- UniProt
- P48200
- Pathways
- Transition Metal Ion Homeostasis
-