This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This APBA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307-336 amino acids from the Central region of human APBA2.
MGC83599 antikoerper, D15S1518E antikoerper, HsT16821 antikoerper, LIN-10 antikoerper, MGC:14091 antikoerper, MINT2 antikoerper, X11-BETA antikoerper, X11L antikoerper, X11-like antikoerper, XllL antikoerper, mXllL antikoerper, Mint2 antikoerper, amyloid beta precursor protein binding family A member 2 antikoerper, amyloid beta (A4) precursor protein-binding, family A, member 2 L homeolog antikoerper, amyloid beta (A4) precursor protein-binding, family A, member 2 antikoerper, APBA2 antikoerper, apba2.L antikoerper, Apba2 antikoerper
Hintergrund
The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].