FAM33A Antikörper (N-Term)

Produktnummer ABIN656609

Produktdetails anti-FAM33A Antikörper

Target: FAM33A (Spindle and Kinetochore-Associated Protein 2 (FAM33A))

Bindungsspezifität: AA 9-37, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAM33A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Pr

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SKA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-37 amino acids from the N-terminal region of human SKA2.

Klon: RB31468

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: SKA2 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu FAM33A

Target: FAM33A (Spindle and Kinetochore-Associated Protein 2 (FAM33A))

Andere Bezeichnung: SKA2 (FAM33A Produkte)

Synonyme: FAM33A antikoerper, 1110001A07Rik antikoerper, C78640 antikoerper, Fam33a antikoerper, RGD1307084 antikoerper, fam33a antikoerper, spindle and kinetochore associated complex subunit 2 antikoerper, Spindle and kinetochore-associated protein 2 antikoerper, SKA2 antikoerper, Ska2 antikoerper, ska2 antikoerper

Hintergrund: Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it is required for SKA1 localization.

Molekulargewicht: 14188

Gen-ID: 348235

NCBI Accession: NP_001094065, NP_872426

UniProt: Q8WVK7

Pathways: M Phase