SPHK1 Antikörper
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- Target Alle SPHK1 Antikörper anzeigen
- SPHK1 (Sphingosine Kinase 1 (SPHK1))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SPHK1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein of human SPHK1
- Isotyp
- IgG
- Top Product
- Discover our top product SPHK1 Primärantikörper
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- Applikationshinweise
- WB 1:500 - 1:2000 IHC 1:50 - 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- SPHK1 (Sphingosine Kinase 1 (SPHK1))
- Andere Bezeichnung
- SPHK1 (SPHK1 Produkte)
- Synonyme
- CG1747 antikoerper, Dmel\\CG1747 antikoerper, SK1 antikoerper, Sphk1 antikoerper, SPHK1 antikoerper, F18E5.160 antikoerper, F18E5_160 antikoerper, sphingosine kinase 1 antikoerper, SPHK antikoerper, 1110006G24Rik antikoerper, Sk1 antikoerper, Spk1 antikoerper, Sphingosine kinase 1 antikoerper, sphingosine kinase 1 antikoerper, sphingosine kinase 1 L homeolog antikoerper, Sk1 antikoerper, SPHK1 antikoerper, sphk1.L antikoerper, Sphk1 antikoerper
- Hintergrund
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Synonyms: SK 1,SK1,Sphingosine kinase 1,SPHK 1,SPHK,Sphk1,SPHK1,SPK ,SPK 1
Background: The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Molekulargewicht
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Observed_MW: 55kDa
Calculated_MW: 42kDa/43kDa/51kDa
- Gen-ID
- 8877
- UniProt
- Q9NYA1
- Pathways
- VEGF Signaling
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