Fibrillarin Antikörper
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- Target Alle Fibrillarin (FBL) Antikörper anzeigen
- Fibrillarin (FBL)
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Reaktivität
- Human, Maus, Affe
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Fibrillarin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein of human FBL
- Isotyp
- IgG
- Top Product
- Discover our top product FBL Primärantikörper
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- Applikationshinweise
- WB 1:500 - 1:2000 IF 1:50 - 1:200 IP 1:50 - 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Fibrillarin (FBL)
- Andere Bezeichnung
- FBL (FBL Produkte)
- Hintergrund
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Synonyms: 34 kD nucleolar scleroderma antigen,34 kDa nucleolar scleroderma antigen,Fbl,FBRL,FIB,FIB1,FLRN,Histone-glutamine methyltransferase,Nop1p,RNA U3 small nucleolar interacting protein 1,RNU3IP1,rRNA 2' O methyltransferase fibrillarin,rRNA 2'-O-methyltransferase fibrillarin
Background: This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8 % of humans with the autoimmune disease scleroderma recognize fibrillarin.
- Molekulargewicht
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Observed_MW: 36kDa
Calculated_MW: 33kDa
- Gen-ID
- 2091
- UniProt
- P22087
- Pathways
- Ribonucleoside Biosynthetic Process
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