ZNF828 Antikörper
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- Target Alle ZNF828 Antikörper anzeigen
- ZNF828 (Zinc Finger Protein 828 (ZNF828))
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ZNF828 Antikörper ist unkonjugiert
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Applikation
- Immunofluorescence (IF)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human CHAMP1 (NP_115812.1).
- Isotyp
- IgG
- Top Product
- Discover our top product ZNF828 Primärantikörper
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- Applikationshinweise
- IF 1:50-1:100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ZNF828 (Zinc Finger Protein 828 (ZNF828))
- Andere Bezeichnung
- CHAMP1 (ZNF828 Produkte)
- Synonyme
- ZNF828 antikoerper, C13orf8 antikoerper, CAMP antikoerper, CHAMP antikoerper, AA675043 antikoerper, AI116001 antikoerper, D8Ertd457e antikoerper, D8Ertd569e antikoerper, Zfp828 antikoerper, Znf828 antikoerper, mKIAA1802 antikoerper, chromosome alignment maintaining phosphoprotein 1 antikoerper, CHAMP1 antikoerper, Champ1 antikoerper
- Hintergrund
- CHAMP1 (chromosome alignment maintaining phosphoprotein 1), also known as ZNF828 or C13orf8, is a 812 amino acid protein containing one C2H2-type zinc finger. CHAMP1 is required for the proper alignment of chromosomes during metaphase, undergoing CDK1-dependent phosphorylation at multiple sites during mitosis. The phosphorylation counteracts the negative chromosomal alignment regulation of the zinc-finger domain of CHAMP1. One region of CHAMP1, the FPE region, is responsible for spindle and kinetochore localization, which is essential for proper chromosome alignment. CHAMP1 interacts with MAD2L2, PGOZ, CBX1, CBX3 and CBX5, and may recruit CENPE and CENPF to the kinetochore. The CHAMP1 gene is located on chromosome 13 and is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat and chicken.
- Molekulargewicht
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Observed_MW: 130kDa
Calculated_MW: 89kDa
- Gen-ID
- 283489
- UniProt
- Q96JM3
- Pathways
- Maintenance of Protein Location
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