Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Homologie
M
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This SEC62 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SEC62.
tloc1 antikoerper, TLOC1 antikoerper, wu:fb57b06 antikoerper, zgc:114073 antikoerper, Dtrp1 antikoerper, HTP1 antikoerper, TP-1 antikoerper, 3100002M17Rik antikoerper, AI844545 antikoerper, AW545092 antikoerper, Tloc1 antikoerper, Ab2-292 antikoerper, SEC62 homolog, preprotein translocation factor S homeolog antikoerper, SEC62 homolog, preprotein translocation factor antikoerper, membrane unit of ER protein translocation apparatus antikoerper, SEC62 homolog (S. cerevisiae) antikoerper, sec62.S antikoerper, SEC62 antikoerper, sec62 antikoerper, Sec62 antikoerper
Hintergrund
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.