DYNC2H1 Antikörper

Produktnummer ABIN6567791

Produktdetails anti-DYNC2H1 Antikörper

Target: DYNC2H1 (Dynein, Cytoplasmic 2, Heavy Chain 1 (DYNC2H1))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DYNC2H1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant Protein of human DYNC2H1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DYNC2H1

Target: DYNC2H1 (Dynein, Cytoplasmic 2, Heavy Chain 1 (DYNC2H1))

Andere Bezeichnung: DYNC2H1 (DYNC2H1 Produkte)

Hintergrund:

Synonyms: Cytoplasmic dynein 2 heavy chain 1,Cytoplasmic dynein 2 heavy chain,DYHC2,DYNC2H1,Dynein cytoplasmic heavy chain 2,Dynein heavy chain 11,Dynein heavy chain isotype 1B,hDHC11

Background: This gene encodes a large cytoplasmic dynein protein that is involved in retrograde transport in the cilium and has a role in intraflagellar transport, a process required for ciliary/flagellar assembly. Mutations in this gene cause a heterogeneous spectrum of conditions related to altered primary cilium function and often involve polydactyly, abnormal skeletogenesis, and polycystic kidneys. Alternative splicing results in multiple transcript variants encoding distinct proteins.

Molekulargewicht:

Observed_MW: 493kDa

Calculated_MW: 105kDa/492kDa/493kDa

Gen-ID: 79659

UniProt: Q8NCM8

Pathways: Hedgehog Signalweg, Asymmetric Protein Localization