IBTK Antikörper
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- Target Alle IBTK Antikörper anzeigen
- IBTK (Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))
- Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IBTK Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein of human IBTK
- Isotyp
- IgG
- Top Product
- Discover our top product IBTK Primärantikörper
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- Applikationshinweise
- WB 1:500 - 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- IBTK (Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))
- Andere Bezeichnung
- IBTK (IBTK Produkte)
- Synonyme
- IBTK antikoerper, fi40c08 antikoerper, wu:fi40c08 antikoerper, DKFZp468J085 antikoerper, BTBD26 antikoerper, BTKI antikoerper, RP1-93K22.1 antikoerper, 5430411K16Rik antikoerper, AA409502 antikoerper, mKIAA1417 antikoerper, inhibitor of Bruton tyrosine kinase antikoerper, inhibitor of Bruton agammaglobulinemia tyrosine kinase antikoerper, inhibitor of Bruton tyrosine kinase L homeolog antikoerper, IBTK antikoerper, ibtk antikoerper, Ibtk antikoerper, ibtk.L antikoerper
- Hintergrund
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Synonyms: BTKI,IBtk,IBTK,inhibitor of Bruton agammaglobulinemia tyrosine kinase,Inhibitor of Bruton tyrosine kinase
Background: Bruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils. The protein encoded by this gene binds to BTK and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- Molekulargewicht
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Observed_MW: 167kDa
Calculated_MW: 26kDa/133kDa/150kDa
- Gen-ID
- 25998
- UniProt
- Q9P2D0
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