IDE Antikörper
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- Target Alle IDE Antikörper anzeigen
- IDE (Insulin-Degrading Enzyme (IDE))
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IDE Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein of human IDE
- Isotyp
- IgG
- Top Product
- Discover our top product IDE Primärantikörper
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- Applikationshinweise
- WB 1:500 - 1:2000 IF 1:10 - 1:100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- IDE (Insulin-Degrading Enzyme (IDE))
- Andere Bezeichnung
- IDE (IDE Produkte)
- Synonyme
- zgc:162603 antikoerper, IDE antikoerper, 1300012G03Rik antikoerper, 4833415K22Rik antikoerper, AA675336 antikoerper, AI507533 antikoerper, INSDEGM antikoerper, INSULYSIN antikoerper, insulin degrading enzyme antikoerper, insulin-degrading enzyme antikoerper, metallopeptidase antikoerper, IDE antikoerper, ide antikoerper, LOC591315 antikoerper, CC1G_01115 antikoerper, Bm1_26615 antikoerper, PTRG_10875 antikoerper, SJAG_01430 antikoerper, EBI_21700 antikoerper, VDBG_06702 antikoerper, LOAG_08082 antikoerper, PGTG_04982 antikoerper, Tsp_00424 antikoerper, Ide antikoerper
- Hintergrund
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Synonyms: Abeta-degrading protease,FLJ35968,Ide,IDE,Insulin protease,Insulin-degrading enzyme,Insulinase,Insulysin,OTTHUMP00000020097
Background: This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.
- Molekulargewicht
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Observed_MW: 118kDa
Calculated_MW: 54kDa/117kDa
- Gen-ID
- 3416
- UniProt
- P14735
- Pathways
- SARS-CoV-2 Protein Interaktom
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