PHD1 Antikörper

Produktnummer ABIN6569199

Produktdetails anti-PHD1 Antikörper

Target: PHD1 (EGLN2) (Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide of human EGLN2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000 IP 1:20 - 1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PHD1

Target: PHD1 (EGLN2) (Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))

Andere Bezeichnung: EGLN2 (EGLN2 Produkte)

Synonyme: egln2 antikoerper, phd2 antikoerper, PHD1 antikoerper, 0610011A13Rik antikoerper, C85656 antikoerper, Hif-p4h-1 antikoerper, Ier4 antikoerper, Phd1 antikoerper, SM-20 antikoerper, HIF-PH1 antikoerper, HPH-1 antikoerper, HPH-3 antikoerper, PHD-1 antikoerper, EIT6 antikoerper, HIFPH1 antikoerper, egl-9 family hypoxia-inducible factor 1 antikoerper, egl-9 family hypoxia inducible factor 2 antikoerper, Egl nine homolog 2 antikoerper, egl-9 family hypoxia-inducible factor 2 L homeolog antikoerper, egl-9 family hypoxia-inducible factor 2 antikoerper, egln1 antikoerper, EGLN2 antikoerper, egln2 antikoerper, egln2.L antikoerper, Egln2 antikoerper

Hintergrund:

Synonyms: DKFZp434E026,EGL nine (C.elegans) homolog 2,Egl nine homolog 2 (C. elegans),Egl nine homolog 2,EGLN 2,EGLN2,EGLN2,EIT 6,EIT6,Estrogen-induced tag 6,HIF P4H 1,HIF PH1,HIF prolyl hydroxylase 1,HIF-PH1,HIF-prolyl hydroxylase 1,HIFPH 1,HIFPH1,HPH 3,HPH-1,HPH-3,HPH3,Hypoxia inducible factor prolyl hydroxylase 1,Hypoxia-inducible factor prolyl hydroxylase 1,P4H1,PHD 1,PhD1,prolyl hydroxylase domain containing protein 1,Prolyl hydroxylase domain-containing protein 1

Background: The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene.

Molekulargewicht:

Observed_MW: 55kDa

Calculated_MW: 40kDa/43kDa

Gen-ID: 112398

UniProt: Q96KS0

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Cell RedoxHomeostasis