CD8B Antikörper
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- Target Alle CD8B Antikörper anzeigen
- CD8B (CD8b Molecule (CD8B))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CD8B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein of human CD8B
- Isotyp
- IgG
- Top Product
- Discover our top product CD8B Primärantikörper
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- Applikationshinweise
- WB 1:200 - 1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CD8B (CD8b Molecule (CD8B))
- Andere Bezeichnung
- CD8B (CD8B Produkte)
- Synonyme
- Cd8b antikoerper, Ly-3 antikoerper, Ly-C antikoerper, Lyt-3 antikoerper, CD8B1 antikoerper, LEU2 antikoerper, LY3 antikoerper, LYT3 antikoerper, P37 antikoerper, Cd8b1 antikoerper, CD8b molecule antikoerper, CD8 antigen, beta chain 1 antikoerper, Cd8b antikoerper, CD8B antikoerper, Cd8b1 antikoerper
- Hintergrund
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Synonyms: CD8b antigen,CD8 antigen beta polypeptide 1 (p37),CD8 antigen beta polypeptide 1,CD8 beta,CD8b,CD8b molecule,CD8B,CD8B1,Leu2,Ly3,LYT3,MGC119115,P37,T cell surface glycoprotein CD8 beta chain,T lymphocyte surface glycoprotein beta chain,T-cell surface glycoprotein CD8 beta chain
Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.
- Molekulargewicht
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Observed_MW: 45kDa
Calculated_MW: 20kDa/22kDa/23kDa/24kDa/25kDa/27kDa
- Gen-ID
- 926
- UniProt
- P10966
- Pathways
- T-Zell Rezeptor Signalweg
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