KREMEN2 Antikörper (AA 248-276)

Produktnummer ABIN656978

Produktdetails anti-KREMEN2 Antikörper

Target: KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))

Bindungsspezifität: AA 248-276

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KREMEN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This KREMEN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-276 amino acids from the Central region of human KREMEN2.

Klon: RB32950

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: KREMEN2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu KREMEN2

Target: KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))

Andere Bezeichnung: KREMEN2 (KREMEN2 Produkte)

Synonyme: krm2 antikoerper, KREMEN2 antikoerper, MGC147633 antikoerper, KRM2 antikoerper, 2900054E04Rik antikoerper, Krm2 antikoerper, kringle containing transmembrane protein 2 S homeolog antikoerper, kringle containing transmembrane protein 2 antikoerper, kremen2.S antikoerper, KREMEN2 antikoerper, kremen2 antikoerper, Kremen2 antikoerper

Hintergrund: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.

Molekulargewicht: 48849

Gen-ID: 79412

NCBI Accession: NP_001240654, NP_001240655, NP_078783, NP_757384

UniProt: Q8NCW0

Pathways: WNT Signalweg