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UNC13B Antikörper (N-Term)

UNC13B Reaktivität: Maus WB Wirt: Kaninchen Polyclonal RB32155 unconjugated
Produktnummer ABIN657040
  • Target Alle UNC13B Antikörper anzeigen
    UNC13B (Unc-13 Homolog B (UNC13B))
    Bindungsspezifität
    • 7
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 263-292, N-Term
    Reaktivität
    • 32
    • 18
    • 3
    Maus
    Wirt
    • 40
    • 3
    • 1
    Kaninchen
    Klonalität
    • 42
    • 2
    Polyklonal
    Konjugat
    • 20
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser UNC13B Antikörper ist unkonjugiert
    Applikation
    • 32
    • 26
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This UNC13B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-292 amino acids from the N-terminal region of human UNC13B.
    Klon
    RB32155
    Isotyp
    Ig Fraction
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    Discover our top product UNC13B Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Target
    UNC13B (Unc-13 Homolog B (UNC13B))
    Andere Bezeichnung
    UNC13B (UNC13B Produkte)
    Synonyme
    MUNC13 antikoerper, UNC13 antikoerper, Unc13h2 antikoerper, UNC13B antikoerper, Munc13-2 antikoerper, Munc13-1 antikoerper, Unc13a antikoerper, Unc13h1 antikoerper, unc-13 homolog B antikoerper, unc-13 homolog B (C. elegans) antikoerper, UNC13B antikoerper, Unc13b antikoerper
    Hintergrund
    This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. [provided by RefSeq].
    Molekulargewicht
    180679
    NCBI Accession
    NP_006368
    UniProt
    O14795
    Pathways
    Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
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