XPC Antikörper
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- Target Alle XPC Antikörper anzeigen
- XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser XPC Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human XPC (NP_004619.3).
- Isotyp
- IgG
- Top Product
- Discover our top product XPC Primärantikörper
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- Applikationshinweise
- IHC 1:50-1:100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))
- Andere Bezeichnung
- XPC (XPC Produkte)
- Synonyme
- RAD4 antikoerper, XP3 antikoerper, XPCC antikoerper, XPC complex subunit, DNA damage recognition and repair factor antikoerper, xeroderma pigmentosum, complementation group C antikoerper, XPC antikoerper, Xpc antikoerper
- Hintergrund
- This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.
- Molekulargewicht
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Observed_MW: 130kDa
Calculated_MW: 15kDa/101kDa/105kDa
- Gen-ID
- 7508
- UniProt
- Q01831
- Pathways
- p53 Signalweg, DNA Reparatur
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