This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This GFRA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-184 amino acids from the Central region of human GFRA4.
GFRA4
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
WB: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Wang, Guo, Wang, Liu, Zhang, Cui, Wu: "Downregulation of microRNA-483-5p Promotes Cell Proliferation and Invasion by Targeting GFRA4 in Hirschsprung's Disease." in: DNA and cell biology, Vol. 36, Issue 11, pp. 930-937, (2017) (PubMed).
zgc:171814 antikoerper, AW060733 antikoerper, G630015H18Rik antikoerper, GDNF family receptor alpha 4 antikoerper, GDNF family receptor alpha 4a antikoerper, glial cell line derived neurotrophic factor family receptor alpha 4 antikoerper, GFRA4 antikoerper, gfra4a antikoerper, Gfra4 antikoerper
Hintergrund
The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for persephin, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for RET-associated diseases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.