Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Homologie
B, M
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This CHMP2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CHMP2B.
ALS17 antikoerper, CHMP2.5 antikoerper, DMT1 antikoerper, VPS2-2 antikoerper, VPS2B antikoerper, 1190006E07Rik antikoerper, RGD1306781 antikoerper, chmp2b antikoerper, chmp2bl antikoerper, zgc:77025 antikoerper, si:ch211-224m9.5 antikoerper, CHMP2B antikoerper, cg4618 antikoerper, chmp2.5 antikoerper, dmt1 antikoerper, vps2-2 antikoerper, vps2b antikoerper, CHMP2b-B antikoerper, chmp2b-a antikoerper, chmp2b-b antikoerper, charged multivesicular body protein 2B antikoerper, charged multivesicular body protein 2Bb antikoerper, charged multivesicular body protein 2Ba antikoerper, charged multivesicular body protein 2B pseudogene antikoerper, charged multivesicular body protein 2B S homeolog antikoerper, charged multivesicular body protein 2B L homeolog antikoerper, CHMP2B antikoerper, Chmp2b antikoerper, chmp2bb antikoerper, chmp2ba antikoerper, LOC747711 antikoerper, chmp2b.S antikoerper, chmp2b.L antikoerper
Hintergrund
This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration.