SGEF Antikörper (AA 378-406)

Produktnummer ABIN657248

Produktdetails anti-SGEF Antikörper

Target: SGEF (ARHGEF26) (rho Guanine Nucleotide Exchange Factor (GEF) 26 (ARHGEF26))

Bindungsspezifität: AA 378-406

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SGEF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SGEF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 378-406 amino acids from the Central region of human SGEF.

Klon: RB33350

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu SGEF

Target: SGEF (ARHGEF26) (rho Guanine Nucleotide Exchange Factor (GEF) 26 (ARHGEF26))

Andere Bezeichnung: SGEF (ARHGEF26 Produkte)

Synonyme: SGEF antikoerper, AI303572 antikoerper, AW491953 antikoerper, 4631416L12Rik antikoerper, 8430436L14Rik antikoerper, RGD1562559 antikoerper, Sgef antikoerper, CSGEF antikoerper, HMFN1864 antikoerper, Rho guanine nucleotide exchange factor (GEF) 26 antikoerper, Rho guanine nucleotide exchange factor 26 antikoerper, Arhgef26 antikoerper, ARHGEF26 antikoerper

Hintergrund: SGEF activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry.

Molekulargewicht: 97346

NCBI Accession: NP_001238891, NP_001238892, NP_056410

UniProt: Q96DR7