SGEF Antikörper (AA 378-406)

Produktnummer ABIN657248

Produktdetails anti-SGEF Antikörper

Target: SGEF (ARHGEF26) (rho Guanine Nucleotide Exchange Factor (GEF) 26 (ARHGEF26))

Bindungsspezifität: AA 378-406

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SGEF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SGEF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 378-406 amino acids from the Central region of human SGEF.

Klon: RB33350

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu SGEF

Target: SGEF (ARHGEF26) (rho Guanine Nucleotide Exchange Factor (GEF) 26 (ARHGEF26))

Andere Bezeichnung: SGEF (ARHGEF26 Produkte)

Hintergrund: SGEF activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry.

Molekulargewicht: 97346

NCBI Accession: NP_001238891, NP_001238892, NP_056410

UniProt: Q96DR7