MARCH4 Antikörper (C-Term)

Produktnummer ABIN657255

Produktdetails anti-MARCH4 Antikörper

Target: MARCH4 (Membrane-Associated Ring Finger (C3HC4) 4, E3 Ubiquitin Protein Ligase (MARCH4))

Bindungsspezifität: AA 302-331, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MARCH4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MARCH4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 302-331 amino acids from the C-terminal region of human MARCH4.

Klon: RB33385

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu MARCH4

Target: MARCH4 (Membrane-Associated Ring Finger (C3HC4) 4, E3 Ubiquitin Protein Ligase (MARCH4))

Andere Bezeichnung: MARCH4 (MARCH4 Produkte)

Synonyme: MARCH-IV antikoerper, RNF174 antikoerper, BC056494 antikoerper, mKIAA1399 antikoerper, MARCH4 antikoerper, si:ch211-239d11.2 antikoerper, membrane associated ring-CH-type finger 4 antikoerper, membrane-associated ring finger (C3HC4) 4 antikoerper, MARCH4 antikoerper, March4 antikoerper, march4 antikoerper

Hintergrund: MARCH4 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266]).

Molekulargewicht: 45528

NCBI Accession: NP_065865

UniProt: Q9P2E8