PRCP Antikörper (N-Term)

Produktnummer ABIN657308

Der Kaninchen Polyklonal Anti-PRCP-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, PRCP in Proben von Human zu detektieren.

Kurzübersicht für PRCP Antikörper (N-Term) (ABIN657308)

Target: PRCP (Prolylcarboxypeptidase (PRCP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRCP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB32742

Produktdetails anti-PRCP Antikörper

Bindungsspezifität: AA 114-143, N-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PRCP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-143 amino acids from the N-terminal region of human PRCP.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu PRCP

Target: PRCP (Prolylcarboxypeptidase (PRCP))

Andere Bezeichnung: PRCP

Hintergrund: The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH , but the enzyme activity is retained with some substrates at neutral pH . This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq].

Molekulargewicht: 55800

NCBI Accession: NP_005031, NP_955450

UniProt: P42785