Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This KCNK18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-197 amino acids from the Central region of human KCNK18.
Two-pore domain potassium channels, such as KCNK18, give rise to background, or leak, potassium conductance, and they regulate diverse cellular functions by adjusting both the resting membrane potential and excitability. KCNK18 is unique among this family of potassium channels in that its activity is regulated by intracellular calcium (summary by Czirjak and Enyedi, 2006 [PubMed 16569637]).