Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Homologie
C
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This TARDBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TARDBP.
TARDBP antikoerper, TDP43 antikoerper, DKFZp459I2127 antikoerper, tardbp antikoerper, ALS10 antikoerper, TDP-43 antikoerper, 1190002A23Rik antikoerper, C85084 antikoerper, Tdp43 antikoerper, wu:fb77f02 antikoerper, wu:fc52g10 antikoerper, TAR DNA binding protein antikoerper, Tardbp protein antikoerper, TAR DNA binding protein L homeolog antikoerper, TAR DNA-binding protein 43-like antikoerper, TARDBP antikoerper, tardbp antikoerper, tardbp.L antikoerper, Tardbp antikoerper, LOC100621383 antikoerper
Hintergrund
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq].