Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This CELA3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-98 amino acids from the N-terminal region of human CELA3B.
CBPP antikoerper, E1 antikoerper, EL-1 antikoerper, ELA3B antikoerper, 0910001F22Rik antikoerper, 2310074F01Rik antikoerper, AI504000 antikoerper, Ela3 antikoerper, Ela3b antikoerper, ela3b antikoerper, MGC82867 antikoerper, ELA1 antikoerper, Cela3b antikoerper, CELA3B antikoerper, chymotrypsin like elastase family member 3B antikoerper, chymotrypsin-like elastase family, member 3B antikoerper, elastase 3B, pancreatic antikoerper, proproteinase E antikoerper, chymotrypsin like elastase family member 3B L homeolog antikoerper, chymotrypsin-like elastase family member 3B antikoerper, CELA3B antikoerper, Cela3b antikoerper, ela3b antikoerper, LOC478196 antikoerper, cela3b.L antikoerper, LOC100717936 antikoerper, LOC100071692 antikoerper
Hintergrund
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays.