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NFKBIB Antikörper (C-Term)

NFKBIB Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB33912 unconjugated
Produktnummer ABIN657702
  • Target Alle NFKBIB Antikörper anzeigen
    NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
    Bindungsspezifität
    • 28
    • 15
    • 13
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 326-355, C-Term
    Reaktivität
    • 113
    • 43
    • 36
    • 9
    • 8
    • 8
    • 7
    • 5
    • 4
    • 1
    • 1
    • 1
    Human
    Wirt
    • 104
    • 10
    Kaninchen
    Klonalität
    • 97
    • 17
    Polyklonal
    Konjugat
    • 55
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser NFKBIB Antikörper ist unkonjugiert
    Applikation
    • 84
    • 41
    • 30
    • 28
    • 27
    • 18
    • 11
    • 7
    • 6
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This NFKBIB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 326-355 amino acids from the C-terminal region of human NFKBIB.
    Klon
    RB33912
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product NFKBIB Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    NFKBIB Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Haltbarkeit
    6 months
  • Target
    NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
    Andere Bezeichnung
    NFKBIB (NFKBIB Produkte)
    Synonyme
    NFKBIB antikoerper, IKB-beta antikoerper, IKappaBbeta antikoerper, IkB antikoerper, IkBb antikoerper, IKBB antikoerper, TRIP9 antikoerper, NFKB inhibitor beta antikoerper, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta antikoerper, NFKBIB antikoerper, Nfkbib antikoerper
    Hintergrund
    NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008, or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664 or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T, R is an A or G purine, and Y is a C or T pyrimidine).
    Molekulargewicht
    37771
    Gen-ID
    4793
    NCBI Accession
    NP_001230045, NP_002494
    UniProt
    Q15653
    Pathways
    NF-kappaB Signalweg, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades
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