NFKBIB Antikörper (C-Term)
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- Target Alle NFKBIB Antikörper anzeigen
- NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
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Bindungsspezifität
- AA 326-355, C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NFKBIB Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This NFKBIB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 326-355 amino acids from the C-terminal region of human NFKBIB.
- Klon
- RB33912
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product NFKBIB Primärantikörper
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anti-NF-kappa-B inhibitor beta (NFKBIB) (pSer23) antibody
NFKBIB Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) antibodyNFKBIB Reaktivität: Human, Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) (AA 1-356) antibodyNFKBIB Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 1G6 unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) (AA 1-356) antibodyNFKBIB Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) antibodyNFKBIB Reaktivität: Human, Maus, Ratte IHC (p), IF Wirt: Maus Monoclonal unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) (AA 56-145) antibodyNFKBIB Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 2B11 unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) (C-Term) antibodyNFKBIB Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) (AA 56-237) antibodyNFKBIB Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) (N-Term) antibodyNFKBIB Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen WB Wirt: Kaninchen Polyclonal unconjugated
anti-NF-kappa-B inhibitor beta (NFKBIB) antibodyNFKBIB Reaktivität: Human ELISA, IHC Wirt: Maus Monoclonal unconjugated
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- Applikationshinweise
- WB: 1:1000. IHC-P: 1:10~50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- NFKBIB Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- Haltbarkeit
- 6 months
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- Target
- NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
- Andere Bezeichnung
- NFKBIB (NFKBIB Produkte)
- Hintergrund
- NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008, or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664 or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T, R is an A or G purine, and Y is a C or T pyrimidine).
- Molekulargewicht
- 37771
- Gen-ID
- 4793
- NCBI Accession
- NP_001230045, NP_002494
- UniProt
- Q15653
- Pathways
- NF-kappaB Signalweg, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades
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