This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This LY6E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from the Central region of human LY6E.
LY6E antikoerper, RIG-E antikoerper, RIGE antikoerper, SCA-2 antikoerper, SCA2 antikoerper, TSA-1 antikoerper, 9804 antikoerper, Ly67 antikoerper, Sca-2 antikoerper, Tsa1 antikoerper, lymphocyte antigen 6 family member E antikoerper, lymphocyte antigen 6 complex, locus E antikoerper, LY6E antikoerper, Ly6e antikoerper
Hintergrund
Sca1, also known as Ly6A/E, is a member of the Ly6 multigene family of type V glycophosphatidylinositol anchored cell surface proteins. It is expressed on multipotent hematopoietic stem cells in bone marrow of mice with both the Ly6.1 and Ly6.2 allotypes. In the periphery, Sca1 exhibits a pattern of expression which is based on differences between the two allotypes. Ly6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have few Sca1+ resting peripheral lymphocytes, whereas Ly6.2 strains (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have relatively high numbers of Sca1+ lymphocytes. The expression of Sca1 is dramatically upregulated in all strains upon cellular activation.