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Nemo-Like Kinase Antikörper (C-Term)

NLK Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB34651 unconjugated
Produktnummer ABIN657850
  • Target Alle Nemo-Like Kinase (NLK) Antikörper anzeigen
    Nemo-Like Kinase (NLK)
    Bindungsspezifität
    • 15
    • 15
    • 8
    • 7
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 408-436, C-Term
    Reaktivität
    • 70
    • 34
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 71
    • 4
    Kaninchen
    Klonalität
    • 72
    • 3
    Polyklonal
    Konjugat
    • 25
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Nemo-Like Kinase Antikörper ist unkonjugiert
    Applikation
    • 67
    • 31
    • 26
    • 26
    • 19
    • 11
    • 10
    • 10
    • 9
    • 6
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    B, Rat
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Mouse Nlk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 408-436 amino acids from the C-terminal region of mouse Nlk.
    Klon
    RB34651
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product NLK Primärantikörper
  • Applikationshinweise
    WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Mouse Nlk Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Haltbarkeit
    6 months
  • Target
    Nemo-Like Kinase (NLK)
    Andere Bezeichnung
    Nlk (NLK Produkte)
    Hintergrund
    Role in cell fate determination, required for differentiation of bone marrow stromal cells. Acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. May suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP. Involved in TGFbeta-mediated mesoderm induction, acting downstream of MAP3K7/TAK1 to phosphorylate STAT3.
    Molekulargewicht
    58313
    Gen-ID
    100044468, 18099
    NCBI Accession
    NP_032728
    UniProt
    O54949
    Pathways
    Ubiquitin Proteasome Pathway
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