p63 Antikörper (C-Term)

Produktnummer ABIN657886

Produktdetails anti-p63 Antikörper

Target: p63 (TP63) (Tumor Protein P63 (TP63))

Bindungsspezifität: AA 651-680, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser p63 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TP63 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 651-680 amino acids from the C-terminal region of human TP63.

Klon: RB30257

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: TP63 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Referenzen für anti-p63 Antikörper (ABIN657886)

Zamudio, Wang, Chung, Wolosin: "Inhibition of TGF? cell signaling for limbal explant culture in serumless, defined xeno-free conditions." in: Experimental eye research, Vol. 145, pp. 48-57, (2015) (PubMed).

Details zu p63

Target: p63 (TP63) (Tumor Protein P63 (TP63))

Andere Bezeichnung: TP63 (TP63 Produkte)

Synonyme: AIS antikoerper, B(p51A) antikoerper, B(p51B) antikoerper, EEC3 antikoerper, KET antikoerper, LMS antikoerper, NBP antikoerper, OFC8 antikoerper, RHS antikoerper, SHFM4 antikoerper, TP53CP antikoerper, TP53L antikoerper, TP73L antikoerper, p40 antikoerper, p51 antikoerper, p53CP antikoerper, p63 antikoerper, p73H antikoerper, p73L antikoerper, TP63 antikoerper, tp63 antikoerper, DNp63 antikoerper, id:ibd3516 antikoerper, tp73l antikoerper, wu:fc89f04 antikoerper, wu:fk85h07 antikoerper, wu:fk88b02 antikoerper, Ket antikoerper, P73l antikoerper, Tp73l antikoerper, Trp63 antikoerper, TRP63 antikoerper, AI462811 antikoerper, P51/P63 antikoerper, P63 antikoerper, Tp63 antikoerper, Trp53rp1 antikoerper, Xp63 antikoerper, ket antikoerper, np63 antikoerper, tp73l-A antikoerper, trp63 antikoerper, tumor protein p63 antikoerper, transformation related protein 63 antikoerper, tumor protein p63 L homeolog antikoerper, TP63 antikoerper, tp63 antikoerper, Tp63 antikoerper, Trp63 antikoerper, tp63.L antikoerper

Hintergrund: This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3), split-hand/foot malformation 4 (SHFM4), ankyloblepharon-ectodermal defects-cleft lip/palate, ADULT syndrome (acro-dermato-ungual-lacrimal-tooth), limb-mammary syndrome, Rap-Hodgkin syndrome (RHS), and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined.

Molekulargewicht: 76785

Gen-ID: 8626

NCBI Accession: NP_001108450, NP_001108451, NP_001108452, NP_001108453, NP_001108454, NP_003713

UniProt: Q9H3D4