C4B Antikörper (AA 655-684)

Produktnummer ABIN657906

Produktdetails anti-C4B Antikörper

Target: C4B (C4b) (Complement Component C4b (C4b))

Bindungsspezifität: AA 655-684

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C4B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: H

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This C4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 655-684 amino acids from the Central region of human C4B.

Klon: RB33642

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: C4B Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu C4B

Target: C4B (C4b) (Complement Component C4b (C4b))

Andere Bezeichnung: C4B (C4b Produkte)

Synonyme: C4B1 antikoerper, C4B12 antikoerper, C4B2 antikoerper, C4B3 antikoerper, C4B5 antikoerper, C4BD antikoerper, C4B_2 antikoerper, C4F antikoerper, CH antikoerper, CO4 antikoerper, CPAMD3 antikoerper, C4 antikoerper, C4A2 antikoerper, C4A3 antikoerper, C4A4 antikoerper, C4A6 antikoerper, C4AD antikoerper, C4S antikoerper, CPAMD2 antikoerper, RG antikoerper, wu:fi14a03 antikoerper, C4B antikoerper, DKFZP469I0332 antikoerper, Slp antikoerper, Ss antikoerper, C4-2 antikoerper, C4l antikoerper, complement C4B (Chido blood group) antikoerper, complement C4A (Rodgers blood group) antikoerper, complement component 4 antikoerper, complement C4-B antikoerper, complement component 4B (Chido blood group) antikoerper, complement component 4A (Rodgers blood group) antikoerper, C4B antikoerper, C4A antikoerper, c4 antikoerper, LOC462577 antikoerper, C4a antikoerper, C4b antikoerper

Hintergrund: This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9.

Molekulargewicht: 192785

Gen-ID: 721

NCBI Accession: NP_001002029, NP_001239133, NP_009224

UniProt: P0C0L4

Pathways: Komplementsystem