CELA2A Antikörper (C-Term)

Produktnummer ABIN657926

Produktdetails anti-CELA2A Antikörper

Target: CELA2A (Chymotrypsin-Like Elastase Family, Member 2A (CELA2A))

Bindungsspezifität: AA 231-260, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CELA2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: Pig

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CELA2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-260 amino acids from the C-terminal region of human CELA2A.

Klon: RB33880

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: CELA2A Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Referenzen für anti-CELA2A Antikörper (ABIN657926)

Guihard, Yao, Blazquez-Medela, Iruela-Arispe, Boström, Yao: "Endothelial-Mesenchymal Transition in Vascular Calcification of Ins2Akita/+ Mice." in: PLoS ONE, Vol. 11, Issue 12, pp. e0167936, (2017) (PubMed).

Yao, Guihard, Blazquez-Medela, Guo, Moon, Jumabay, Boström, Yao: "Serine Protease Activation Essential for Endothelial-Mesenchymal Transition in Vascular Calcification." in: Circulation research, Vol. 117, Issue 9, pp. 758-69, (2015) (PubMed).

Details zu CELA2A

Target: CELA2A (Chymotrypsin-Like Elastase Family, Member 2A (CELA2A))

Andere Bezeichnung: CELA2A (CELA2A Produkte)

Hintergrund: Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Like most of the human elastases, elastase 2A is secreted from the pancreas as a zymogen. In other species, elastase 2A has been shown to preferentially cleave proteins after leucine, methionine, and phenylalanine residues.

Molekulargewicht: 28888

Gen-ID: 63036

NCBI Accession: NP_254275

UniProt: P08217