CIDEA Antikörper (C-Term)

Produktnummer ABIN657978

Produktdetails anti-CIDEA Antikörper

Target: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Bindungsspezifität: AA 181-209, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CIDEA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CIDEA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-209 amino acids from the C-terminal region of human CIDEA.

Klon: RB34139

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: CIDEA Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu CIDEA

Target: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Andere Bezeichnung: CIDEA (CIDEA Produkte)

Synonyme: CIDE-A antikoerper, AW212747 antikoerper, CIDEA antikoerper, cide-a antikoerper, MGC89985 antikoerper, cell death-inducing DFFA-like effector a antikoerper, cell death-inducing DNA fragmentation factor, alpha subunit-like effector A antikoerper, cell death-inducing DFFA-like effector a L homeolog antikoerper, CIDEA antikoerper, Cidea antikoerper, cidea antikoerper, cidea.L antikoerper

Hintergrund: This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.

Molekulargewicht: 24687

Gen-ID: 1149

NCBI Accession: NP_001270

UniProt: O60543