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DYRK2 Antikörper (C-Term)

DYRK2 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB34467 unconjugated
Produktnummer ABIN657991
  • Target Alle DYRK2 Antikörper anzeigen
    DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))
    Bindungsspezifität
    • 15
    • 10
    • 8
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 521-549, C-Term
    Reaktivität
    • 42
    • 31
    • 22
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 55
    • 7
    • 1
    Kaninchen
    Klonalität
    • 56
    • 7
    Polyklonal
    Konjugat
    • 26
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DYRK2 Antikörper ist unkonjugiert
    Applikation
    • 56
    • 33
    • 27
    • 13
    • 13
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Mouse Dyrk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 521-549 amino acids from the C-terminal region of mouse Dyrk2.
    Klon
    RB34467
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product DYRK2 Primärantikörper
  • Applikationshinweise
    WB: 1:2000. WB: 1:1000. WB: 1:8000. IHC-P: 1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Mouse Dyrk2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Haltbarkeit
    6 months
  • Target
    DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))
    Andere Bezeichnung
    Dyrk2 (DYRK2 Produkte)
    Synonyme
    DYRK2 antikoerper, fc18c09 antikoerper, si:ch211-266a5.8 antikoerper, wu:fa09g03 antikoerper, wu:fc18c09 antikoerper, 1810038L18Rik antikoerper, dual specificity tyrosine phosphorylation regulated kinase 2 antikoerper, dual specificity tyrosine-phosphorylation-regulated kinase 2 antikoerper, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 antikoerper, DYRK2 antikoerper, CpipJ_CPIJ014802 antikoerper, dyrk2 antikoerper, Dyrk2 antikoerper
    Hintergrund
    Role in the regulation of cellular growth and/or development. Regulates TP53 by phosphorylation on Ser-46 to induce apoptosis in response to DNA damage, functioning downstream of ATM. Inactivates GYS1 by phosphorylation at Ser-641, and potentially also a second phosphorylation site, thus regulating glycogen synthesis. Phosphorylates EIF2B5 at Ser-544, enabling its subsequent phosphorylation and inhibition by GSK3, and may play a more general role in the priming of GSK3 substrates (By similarity).
    Molekulargewicht
    66556
    Gen-ID
    69181
    NCBI Accession
    NP_001014412
    UniProt
    Q5U4C9
    Pathways
    Regulation of Carbohydrate Metabolic Process
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