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Anthrax Protective Antigen Antikörper (Internal Region)

PA Reaktivität: Bacillus anthracis WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6655029
  • Target Alle Anthrax Protective Antigen (PA) Produkte
    Anthrax Protective Antigen (PA)
    Bindungsspezifität
    • 2
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 13
    • 2
    Bacillus anthracis
    Wirt
    • 8
    • 4
    • 2
    • 1
    Kaninchen
    Klonalität
    • 8
    • 7
    Polyklonal
    Konjugat
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Anthrax Protective Antigen Antikörper ist unkonjugiert
    Applikation
    • 14
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    Anti-Anthrax Protective Antigen Antibody is sera. A BLAST analysis was used to suggest cross-reactivity with Anti-Anthrax PA from multiple species based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-Anthrax PA from other sources has not been determined.
    Immunogen

    Immunogen: Anthrax Protective Antigen Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to the internal region of the Anthrax PA protein.

    Immunogen Type: Peptide

  • Applikationshinweise

    Application Note: Anti-Anthrax PA (Protective Antigen) Antibody is suitable for use in WB. Expect a band approximately 83 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

    Western Blot Dilution: 1:100-1:1000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 0.05 % BSA

    0.05 % (w/v) Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    RT,4 °C,-20 °C
    Informationen zur Lagerung
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
  • Target
    Anthrax Protective Antigen (PA)
    Andere Bezeichnung
    Anthrax Protective Antigen (PA Produkte)
    Hintergrund

    Synonyms: pag, Anthrax Protective Antigen, Anthrax toxins translocating protein, PA-83, Protective antigen PA-20, PA20, Protective antigen PA-63, PA63

    Background: Anthrax PA (Protective Antigen) and Anthrax LF (Lethal Factor), along with Anthrax EF (Edema Factor), are toxins produced by Bacillus anthracis. All three of the proteins must be present for toxic entry into cells. Anthrax PA is secreted from Bacillus anthracis as an 83 kD (PA83) protein which is cleaved by furin protease, releasing a 20 kD fragment. The 63 kD portion (PA63) of the cleavage product forms a heptamer, which binds the toxins LF and EF. This complex enters via receptor-mediated endocytosis where LF and EF exert their toxic effects. Anthrax PA is ideal for researchers interested in Neurobiology research.

    Gene Name: pagA

    Gen-ID
    1158723
    NCBI Accession
    NP_052806
    UniProt
    P13423
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