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ABCA4 Antikörper

Rockland 200-301-d05 ABCA4 Reaktivität: Rind (Kuh) WB, ELISA, IHC Wirt: Maus Monoclonal 3F4 unconjugated
Rockland
Produktnummer ABIN6655047
Hersteller Produkt- Nr.: 200-301-d05
  • Target Alle ABCA4 Antikörper anzeigen
    ABCA4 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4))
    Reaktivität
    • 21
    • 10
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Rind (Kuh)
    Wirt
    • 19
    • 4
    • 2
    Maus
    Klonalität
    • 22
    • 3
    Monoklonal
    Konjugat
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ABCA4 Antikörper ist unkonjugiert
    Applikation
    • 15
    • 9
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Hersteller Produkt- Nr.
    200-301-d05
    Hersteller
    Rockland
    Verwendungszweck
    ABCA4 Rim Protein Antibody
    Kreuzreaktivität (Details)
    Anti-ABCA4 antibody is directed against bovine ABCA4 Rim Protein.
    Aufreinigung
    The antibody was Protein G purified from culture supernatant.
    Immunogen
    Anti-ABCA4 antibody was produced by repeated immunizations with 220-kDa (full length) partially purified native bovine disc rim protein.
    Klon
    3F4
    Isotyp
    IgG
    Top Product
    Discover our top product ABCA4 Primärantikörper
  • Applikationshinweise

    ELISA_Dilution: 1:10,000

    Immunohistochemistry_Dilution: 1:100

    Western_Blot_Dilution: 1:1000

    Kommentare

    Suggested Applications: IF
    Anti-ABCA4 antibody has been tested by western blot and IHC and is suitable for use in ELISA. Specific conditions should be optimized by the end user. Expect a band of ~220kDa in size corresponding to ABCA4 proteins in the appropriate cell lysate or extract.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer

    Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

    Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
    Haltbarkeit
    12 months
  • Target
    ABCA4 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4))
    Andere Bezeichnung
    ABCA4 Rim Protein (ABCA4 Produkte)
    Hintergrund

    Synonyms: Retinal-specific ATP-binding cassette transporter, ATP-binding cassette sub-family A member 4, RIM ABC transporter

    Background: ABCA4 antibody detects ABCA4 (ATP-binding cassette, sub-family A (ABC1), member 4, Rim Protein) a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABCA4 is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essential molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease and are associated with retinitis pigmentosa-19 and age-related macular degeneration. Defects in ABCA4 are the cause of Stargardt disease type 1 (STGD1). STGD is one of the most frequent causes of macular degeneration in childhood. Defects in ABCA4 are also known to cause fundus flavimaculatus (FFM), age-related macular degeneration type 2 (ARMD2) and cone-rod dystrophy type 3 (CORD3). Anti-ABCA4 antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

    Gene Name: ABCA4

    Gen-ID
    11304
    NCBI Accession
    NP_776646
    UniProt
    O35600
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