APP Antikörper
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- Target Alle APP Antikörper anzeigen
- APP (Amyloid beta (A4) Precursor Protein (APP))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser APP Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- Hersteller Produkt- Nr.
- 200-401-e87
- Hersteller
- Rockland
- Verwendungszweck
- Amyloid Fibrils (OC) Antibody
- Kreuzreaktivität (Details)
- A BLAST analysis was used to suggest cross-reactivity with Amyloid Fibrils (OC) from Human based on 100 % homology with the immunizing sequence.
- Aufreinigung
- Anti-Amyloid Fibrils (OC) Antibody was purified by Protein A chromatography.
- Sterilität
- Sterile filtered
- Immunogen
- Amyloid Fibrils (OC) Antibody was produced from whole rabbit serum prepared by repeated immunizations with fibrils prepared from human Abeta42 synthetic peptide.
- Isotyp
- IgG
- Top Product
- Discover our top product APP Primärantikörper
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- Applikationshinweise
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Immunoprecipitation_Dilution: User Optimized
ELISA_Dilution: 1:200
Immunohistochemistry_Dilution: User Optimized
Western_Blot_Dilution: 1:1000
- Kommentare
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Suggested Applications: Other
Anti-Amyloid Fibrils (OC) Antibody is tested for use in IP, IF microscopy, IHC, and WB. Specific conditions for reactivity should be optimized by the end user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
Preservative: 0.09 % (w/v) Sodium Azide - Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- Haltbarkeit
- 12 months
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- Target
- APP (Amyloid beta (A4) Precursor Protein (APP))
- Andere Bezeichnung
- APP (APP Produkte)
- Hintergrund
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Synonyms: Amyloid OC, Fibrils, Amyloid Oligomer αβ, A11, Amyloid beta A4 protein, ABPP, APPI, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, PreA4, Protease nexin-II, APP, A4, AD1
Background: Amyloid monomeric proteins can sometimes oligomerize into destructive amyloid fibrils. Amyloidogenic conformations of non-disease related proteins can be created by partial protein misfolding or denaturation. Many degenerative diseases are known to be related to the accumulation of misfolded proteins as amyloid fibres. These include the amyloid-β peptide plaques and tau neurofibrillary tangles in senile plaques of Alzheimer's symptomology, the deposition of α-synuclein in the Lewy bodies of Parkinson's disease, and accumulation of polyglutamine-containing aggregates in Huntington's disease.
Gene Name: APP
- UniProt
- P05067
- Pathways
- Caspase Kaskade in der Apoptose, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour
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