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APP Antikörper

Rockland 200-401-e87 APP Reaktivität: Human WB, ELISA, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated
Rockland
Produktnummer ABIN6655141
Hersteller Produkt- Nr.: 200-401-e87
  • Target Alle APP Antikörper anzeigen
    APP (Amyloid beta (A4) Precursor Protein (APP))
    Reaktivität
    • 229
    • 110
    • 106
    • 12
    • 10
    • 10
    • 9
    • 9
    • 9
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 194
    • 73
    • 4
    • 4
    • 1
    Kaninchen
    Klonalität
    • 212
    • 64
    Polyklonal
    Konjugat
    • 142
    • 24
    • 19
    • 18
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser APP Antikörper ist unkonjugiert
    Applikation
    • 177
    • 127
    • 74
    • 52
    • 52
    • 44
    • 38
    • 29
    • 28
    • 15
    • 14
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    Hersteller Produkt- Nr.
    200-401-e87
    Hersteller
    Rockland
    Verwendungszweck
    Amyloid Fibrils (OC) Antibody
    Kreuzreaktivität (Details)
    A BLAST analysis was used to suggest cross-reactivity with Amyloid Fibrils (OC) from Human based on 100 % homology with the immunizing sequence.
    Aufreinigung
    Anti-Amyloid Fibrils (OC) Antibody was purified by Protein A chromatography.
    Sterilität
    Sterile filtered
    Immunogen
    Amyloid Fibrils (OC) Antibody was produced from whole rabbit serum prepared by repeated immunizations with fibrils prepared from human Abeta42 synthetic peptide.
    Isotyp
    IgG
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    Discover our top product APP Primärantikörper
  • Applikationshinweise

    Immunoprecipitation_Dilution: User Optimized

    ELISA_Dilution: 1:200

    Immunohistochemistry_Dilution: User Optimized

    Western_Blot_Dilution: 1:1000

    Kommentare

    Suggested Applications: Other
    Anti-Amyloid Fibrils (OC) Antibody is tested for use in IP, IF microscopy, IHC, and WB. Specific conditions for reactivity should be optimized by the end user.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 50 % (v/v) Glycerol

    Preservative: 0.09 % (w/v) Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    Haltbarkeit
    12 months
  • Target
    APP (Amyloid beta (A4) Precursor Protein (APP))
    Andere Bezeichnung
    APP (APP Produkte)
    Hintergrund

    Synonyms: Amyloid OC, Fibrils, Amyloid Oligomer αβ, A11, Amyloid beta A4 protein, ABPP, APPI, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, PreA4, Protease nexin-II, APP, A4, AD1

    Background: Amyloid monomeric proteins can sometimes oligomerize into destructive amyloid fibrils. Amyloidogenic conformations of non-disease related proteins can be created by partial protein misfolding or denaturation. Many degenerative diseases are known to be related to the accumulation of misfolded proteins as amyloid fibres. These include the amyloid-β peptide plaques and tau neurofibrillary tangles in senile plaques of Alzheimer's symptomology, the deposition of α-synuclein in the Lewy bodies of Parkinson's disease, and accumulation of polyglutamine-containing aggregates in Huntington's disease.

    Gene Name: APP

    UniProt
    P05067
    Pathways
    Caspase Kaskade in der Apoptose, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour
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