TBPL1 Antikörper

Produktnummer ABIN6655376

Produktdetails anti-TBPL1 Antikörper

Target: TBPL1 (TBP-Like 1 (TBPL1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TBPL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS), Chromatin Immunoprecipitation (ChIP), Fluorescence Microscopy (FM)

Aufreinigung: Anti-TRF2 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-TRF2 from Human, Mouse, Muntjac (deer), and rat based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-TRF2 from other sources has not been determined.

Immunogen:

Immunogen: TRF2 Antibody was produced in mice by repeated immunizations with a full-length TRF2 human protein.

Immunogen Type: Recombinant Protein

Klon: 4A794-15

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry Dilution: 5 μg/mL

Application Note: Anti-TRF2 Antibody is suitable for use in ChIP, ELISA, Flow (Intracellular) Cytometry, IF/ICC, IHC (frozen), IP, and WB. Expect a band approximately 55.6 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

ChIP Dilution: User Optimized

Immunoprecipitation Dilution: 2 μg/10^6 cells

ELISA Dilution: 2 μg/mL

Flow Cytometry Dilution: User Optimized

Western Blot Dilution: 2-4 μg/mL

IF Microscopy Dilution: User Optimized

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 0.05 % BSA

0.05 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: RT,4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Details zu TBPL1

Target: TBPL1 (TBP-Like 1 (TBPL1))

Andere Bezeichnung: TRF2 (TBPL1 Produkte)

Synonyme: MGC:8389 antikoerper, MGC:9620 antikoerper, STUD antikoerper, TLF antikoerper, TLP antikoerper, TRF2 antikoerper, tlf antikoerper, 4732475G08 antikoerper, AW011832 antikoerper, AW491032 antikoerper, D18347 antikoerper, STD antikoerper, TRP antikoerper, Tlp antikoerper, tlp antikoerper, trf antikoerper, trf2 antikoerper, trp antikoerper, zgc:92340 antikoerper, TATA binding protein 1 antikoerper, TFIID-1 antikoerper, TRANSCRIPTION FACTOR IID-1 antikoerper, TATA-box binding protein like 1 antikoerper, TATA-binding protein 1 antikoerper, TATA-box binding protein like 1 L homeolog antikoerper, TATA box binding protein-like 1 antikoerper, TBP-like 1 antikoerper, TATA binding protein 1 antikoerper, TBPL1 antikoerper, tbp1 antikoerper, tbpl1.L antikoerper, tbpl1 antikoerper, Tbpl1 antikoerper, TBP1 antikoerper

Hintergrund:

Synonyms: TRBF2, TRF2, Telomeric repeat-binding factor 2, TTAGGG repeat-binding factor 2, Telomeric DNA-binding protein

Background: TRF2 antibody detects human, mouse, deer and rat TRF2. TRF2 is an ubiquitously expressed protein that is implicated in the control of telomere length. TRF2, like TRF1, contains a Myb-related DNA binding motif. It binds to duplex TTAGGG repeats and is localized to all human telomeres in metaphase chromosomes. TRF2 is thought to protect chromosome ends by maintaining the correct structure at telomere termini. The use of mutant forms of TRF2 has implicated a role for TRF2 in the prevention of senescence in primary human cells. Recently, it has been shown that inhibition of TRF2 resulted in apoptosis in a subset of mammalian cell types. Anti TRF2 antibody is ideal for investigators involved in apoptosis and chromatin research.

Gene Name: TERF2

Gen-ID: 7014

NCBI Accession: NP_005643

UniProt: Q15554