DUX4 Antikörper (C-Term)

Produktnummer ABIN6655475

Hersteller Produkt- Nr.: 209-301-f23

Produktdetails anti-DUX4 Antikörper

Target: DUX4 (Double Homeobox 4 (DUX4))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DUX4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Fluorescence Microscopy (FM)

Hersteller Produkt- Nr.: 209-301-f23

Hersteller: Rockland

Verwendungszweck: DUX4 Antibody

Kreuzreaktivität (Details): This monoclonal antibody is specific for human DUX4 protein.

Aufreinigung: Anti-DUX4 Antibody was purified by Protein G chromatography.

Sterilität: Sterile filtered

Immunogen: DUX4 Antibody was produced in mice by repeated immunizations with a recombinant protein corresponding to the C-terminal region of human DUX4 protein.

Klon: P2B1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry_Dilution: User Optimized

IF_Microscopy_Dilution: User Optimized

Western_Blot_Dilution: 1:1000

Kommentare:

Anti-DUX4 Antibody is tested for use in WB and IF and suitable for IHC. Specific conditions for reactivity should be optimized by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu DUX4

Target: DUX4 (Double Homeobox 4 (DUX4))

Andere Bezeichnung: DUX4 (DUX4 Produkte)

Hintergrund:

Synonyms: mouse anti-DUX4 Antibody, double homeobox 4, DUX4, Double homeobox protein 4-like protein, DUX4L2, DUX4L3, DUX4L5, DUX4L6, DUX4L7

Background: DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1. Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function. In FSHD individuals, the expression of the full-length DUX4 transcipt is not completely suppressed in skeletal muscle and possibly other differentiated tissues.

Gene Name: DUX2

Gen-ID: 100288687

NCBI Accession: NP_001280727

UniProt: Q9UBX2