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TNFAIP3 Antikörper (C-Term)

Rockland 200-301-h52 TNFAIP3 Reaktivität: Human WB, IHC, IF, IP, FACS Wirt: Maus Monoclonal 59A426 unconjugated
Rockland
Produktnummer ABIN6655643
Hersteller Produkt- Nr.: 200-301-h52
  • Target Alle TNFAIP3 Antikörper anzeigen
    TNFAIP3 (Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3))
    Bindungsspezifität
    • 15
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 57
    • 31
    • 25
    • 4
    • 1
    Human
    Wirt
    • 51
    • 5
    • 1
    Maus
    Klonalität
    • 43
    • 14
    Monoklonal
    Konjugat
    • 24
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TNFAIP3 Antikörper ist unkonjugiert
    Applikation
    • 22
    • 15
    • 14
    • 13
    • 8
    • 8
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)
    Hersteller Produkt- Nr.
    200-301-h52
    Hersteller
    Rockland
    Verwendungszweck
    A20 Antibody
    Kreuzreaktivität (Details)
    A BLAST analysis was used to suggest cross-reactivity with Anti-A20 from Human, Mouse and rat based on 100 % homology with the immunizing sequence.
    Aufreinigung
    Anti-A20 Antibody was purified by Protein G chromatography.
    Immunogen
    A20 Antibody was produced in mice by repeated immunizations with recombinant human A20 protein at the c-terminus.
    Klon
    59A426
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product TNFAIP3 Primärantikörper
  • Applikationshinweise

    Immunoprecipitation_Dilution: 1-2 μg/mL

    Western_Blot_Dilution: 2-4 μg/mL

    Kommentare

    Anti-A20 antibody is tested for use in WB, Flow, Flow-IC, ICC/IF, IHC, IHC-P, and IP. Expect a band approximately 90kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 0.05 % BSA

    Preservative: 0.05 % (w/v) Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    Haltbarkeit
    12 months
  • Target
    TNFAIP3 (Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3))
    Andere Bezeichnung
    TNFAIP3 (TNFAIP3 Produkte)
    Hintergrund

    Synonyms: OTUD7C, Tumor necrosis factor alpha-induced protein 3, TNF alpha-induced protein 3, OTU domain-containing protein 7C, A20p50, A20p37

    Background: Anti-A20 antibody detects human A20. A20 (TNFAIP3) is an important regulator of proinflammatory signaling pathways, including NK-kB sginaling. A20 is upregulated through NF-kB (p50/p55) activation, and subsequently down regulates NF-kB through its dual function as a deubiquitinase and ubiquitin ligase. The A20 monoclonal antibody has been instrumental in discovering various nuances of NF-kB regulation and key to defining A20 biology. Anti-A20 antibody is ideal for investigators involved in NFkappaB and Signaling research.

    Gene Name: TNFAIP3

    Gen-ID
    7128
    NCBI Accession
    NP_001257436
    UniProt
    P21580
    Pathways
    TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Production of Molecular Mediator of Immune Response
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