TNFAIP3 Antikörper (C-Term)
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- Target Alle TNFAIP3 Antikörper anzeigen
- TNFAIP3 (Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser TNFAIP3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)
- Hersteller Produkt- Nr.
- 200-301-h52
- Hersteller
- Rockland
- Verwendungszweck
- A20 Antibody
- Kreuzreaktivität (Details)
- A BLAST analysis was used to suggest cross-reactivity with Anti-A20 from Human, Mouse and rat based on 100 % homology with the immunizing sequence.
- Aufreinigung
- Anti-A20 Antibody was purified by Protein G chromatography.
- Immunogen
- A20 Antibody was produced in mice by repeated immunizations with recombinant human A20 protein at the c-terminus.
- Klon
- 59A426
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product TNFAIP3 Primärantikörper
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- Applikationshinweise
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Immunoprecipitation_Dilution: 1-2 μg/mL
Western_Blot_Dilution: 2-4 μg/mL
- Kommentare
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Anti-A20 antibody is tested for use in WB, Flow, Flow-IC, ICC/IF, IHC, IHC-P, and IP. Expect a band approximately 90kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.05 % BSA
Preservative: 0.05 % (w/v) Sodium Azide - Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- Haltbarkeit
- 12 months
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- Target
- TNFAIP3 (Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3))
- Andere Bezeichnung
- TNFAIP3 (TNFAIP3 Produkte)
- Hintergrund
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Synonyms: OTUD7C, Tumor necrosis factor alpha-induced protein 3, TNF alpha-induced protein 3, OTU domain-containing protein 7C, A20p50, A20p37
Background: Anti-A20 antibody detects human A20. A20 (TNFAIP3) is an important regulator of proinflammatory signaling pathways, including NK-kB sginaling. A20 is upregulated through NF-kB (p50/p55) activation, and subsequently down regulates NF-kB through its dual function as a deubiquitinase and ubiquitin ligase. The A20 monoclonal antibody has been instrumental in discovering various nuances of NF-kB regulation and key to defining A20 biology. Anti-A20 antibody is ideal for investigators involved in NFkappaB and Signaling research.
Gene Name: TNFAIP3
- Gen-ID
- 7128
- NCBI Accession
- NP_001257436
- UniProt
- P21580
- Pathways
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Production of Molecular Mediator of Immune Response
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