KDM5C Antikörper

Produktnummer ABIN6655941

Hersteller Produkt- Nr.: 100-401-w42

Produktdetails anti-KDM5C Antikörper

Target: KDM5C (Lysine (K)-Specific Demethylase 5C (KDM5C))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KDM5C Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Hersteller Produkt- Nr.: 100-401-w42

Hersteller: Rockland

Verwendungszweck: JARID1C Antibody

Kreuzreaktivität (Details): Cross reactivity with Jarid1c from other species not tested.

Aufreinigung: Anti-Jarid1c Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.

Sterilität: Sterile filtered

Immunogen: Anti-JARID1C Antibody was produced in rabbits by repeated immunizations with three different synthetic peptides containing sequences from the inner part of the mouse Jarid1c protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

ELISA_Dilution: 1:500

Western_Blot_Dilution: 1:1,000

Kommentare:

Anti-JARID1C Antibody has been tested by ELISA and Western Blots. Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 175 kDa in the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: None

Stabilizer: None

Preservative: 0.05 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu KDM5C

Target: KDM5C (Lysine (K)-Specific Demethylase 5C (KDM5C))

Andere Bezeichnung: Jarid1c (KDM5C Produkte)

Hintergrund:

Synonyms: Lysine-specific demethylase 5C, Histone demethylase JARID1C, Jumonji/ARID domain-containing protein 1C, Protein SmcX, Protein Xe169, DXS1272E, JARID1C, SMCX, XE169

Background: Jarid1c is a histone demethylase which specifically demethylates lysine 4 of histone H3, thereby playing a internal role in the regulation of transcription and chromatin remodelling. Jarid1c demethylates the trimethylated and dimethylated lysine 4, but not the monomethylated form. Further, Jarid1c participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Mutations in the Jarid1c gene have been associated with X-linked mental retardation. Anti-Jarid1c Antibody is ideal for research in Epigenetics, Gene Expression and Neuroscience.

Gene Name: KDM5C

Gen-ID: 8242

NCBI Accession: NP_001140174

UniProt: P41229

Pathways: Warburg Effekt