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KDELR1 Antikörper

Rockland 600-401-f85 KDELR1 Reaktivität: Human WB, IF, IHC Wirt: Kaninchen Polyclonal unconjugated
Rockland
Produktnummer ABIN6656145
Hersteller Produkt- Nr.: 600-401-f85
  • Target Alle KDELR1 Antikörper anzeigen
    KDELR1 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 1 (KDELR1))
    Reaktivität
    • 15
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 14
    • 3
    Kaninchen
    Klonalität
    • 13
    • 4
    Polyklonal
    Konjugat
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KDELR1 Antikörper ist unkonjugiert
    Applikation
    • 17
    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
    Hersteller Produkt- Nr.
    600-401-f85
    Hersteller
    Rockland
    Verwendungszweck
    KDEL Antibody
    Kreuzreaktivität (Details)
    A BLAST analysis was used to suggest cross-reactivity with KDEL from Human, Mouse, and Rat based on 100 % homology with the immunizing sequence.
    Aufreinigung
    Anti-KDEL Antibody was purified by affinity chromatography.
    Sterilität
    Sterile filtered
    Immunogen
    KDEL Antibody was produced from whole rabbit serum prepared by repeated immunizations raised against KDEL containing synthetic peptide immunogen.
    Isotyp
    IgG
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  • Applikationshinweise
    Optional[Neutralization_Dilution]: 1:1000
    Kommentare

    Anti-KDEL Antibody is tested for use in WB, IF, and IHC. Specific conditions for reactivity should be optimized by the end user.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 50 % (v/v) Glycerol

    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    Haltbarkeit
    12 months
  • Target
    KDELR1 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 1 (KDELR1))
    Andere Bezeichnung
    KDELR1 (KDELR1 Produkte)
    Hintergrund

    Synonyms: Lys Asp Glu Leu, K-D-E-L, ER lumen protein retaining receptor 1, KDEL endoplasmic reticulum protein retention, Kdelr1

    Background: The endoplasmic reticulum is part of a protein sorting pathway, or in essence, the transportation system of the eukaryotic cell. The majority of endoplasmic reticulum resident proteins are retained in the endoplasmic reticulum through a retention motif. This motif is composed of four amino acids at the C-terminal end of the protein sequence. The most common retention sequence is KDEL (lys-asp-glu-leu). Grp78 and Grp94 and PDI all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER.

    Gene Name: Kdelr1

    Gen-ID
    10945
    NCBI Accession
    NP_006792
    UniProt
    P24390
    Pathways
    Maintenance of Protein Location
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