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AQP2 Antikörper (C-Term)

Rockland 600-401-e90 AQP2 Reaktivität: Ratte WB, IHC, IF, FM Wirt: Kaninchen Polyclonal unconjugated
Rockland
Produktnummer ABIN6656925
Hersteller Produkt- Nr.: 600-401-e90
  • Target Alle AQP2 Antikörper anzeigen
    AQP2 (Aquaporin 2 (Collecting Duct) (AQP2))
    Bindungsspezifität
    • 21
    • 20
    • 17
    • 16
    • 15
    • 15
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 109
    • 96
    • 80
    • 15
    • 15
    • 10
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Ratte
    Wirt
    • 131
    • 2
    Kaninchen
    Klonalität
    • 131
    • 3
    Polyklonal
    Konjugat
    • 47
    • 10
    • 9
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser AQP2 Antikörper ist unkonjugiert
    Applikation
    • 115
    • 41
    • 41
    • 40
    • 30
    • 20
    • 20
    • 17
    • 16
    • 15
    • 7
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Fluorescence Microscopy (FM)
    Hersteller Produkt- Nr.
    600-401-e90
    Hersteller
    Rockland
    Verwendungszweck
    Aquaporin 2 Antibody
    Kreuzreaktivität (Details)
    A BLAST analysis was used to suggest cross-reactivity with Aquaporin 2 from Human, Mouse, and Rat based on 100 % homology with the immunizing sequence.
    Aufreinigung
    Anti-Aquaporin 2 Antibody was purified by affinity chromatography.
    Sterilität
    Sterile filtered
    Immunogen
    Aquaporin 2 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to the C-terminal region of rat aquaporin 2.
    Isotyp
    IgG
    Top Product
    Discover our top product AQP2 Primärantikörper
  • Applikationshinweise

    Immunohistochemistry_Dilution: 1:200

    IF_Microscopy_Dilution: 1:400

    Western_Blot_Dilution: 1:1000 - 1:4000

    Kommentare

    Anti-Aquaporin 2 Antibody is tested for use in WB, IHC, and IF microscopy. Expect a band approximately ~28.5kDa on specific lysates. May detect larger glycosylated bands ~35-50kDa. Specific conditions for reactivity should be optimized by the end user.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 50 % (v/v) Glycerol

    Preservative: 0.1 % (w/v) Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    Haltbarkeit
    12 months
  • Target
    AQP2 (Aquaporin 2 (Collecting Duct) (AQP2))
    Andere Bezeichnung
    Aquaporin 2 (AQP2 Produkte)
    Hintergrund

    Synonyms: AQP2, AQP-CD, AQPCD, WCH CD, Aquaporin-2, AQP-2, ADH water channel, Aquaporin-CD, QP-CD, Collecting duct water channel protein, WCH-CD, Water channel protein for renal collecting duct

    Background: Aquaporins selectively conduct water molecules in and out of the cell, while preventing the passage of ions and other solutes. Known as water channels, they are integral membrane pore proteins. Aquaporin 2 is the vasopressin-regulated water channel of the apical membrane of collecting duct cells. It is located in kidney epithelial cells and usually lies dormant in intracellular vesicle membranes. When it is needed vasopressin binds to the cell surface vasopressin receptor, activating a signaling pathway that cause AQP2 containing vesicles to fuse with the plasma membrane so the AQP2 can be used by the cell. Defects in AQP2 area cause of an autosomal dominant form of nephrogenic diabetes insipidus (NDI).

    Gene Name: Aqp2

    Gen-ID
    25386
    NCBI Accession
    NP_037041
    UniProt
    P34080
    Pathways
    Response to Water Deprivation
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