AQP3 Antikörper (C-Term)

Produktnummer ABIN6656926

Hersteller Produkt- Nr.: 600-401-e91

Produktdetails anti-AQP3 Antikörper

Target: AQP3 (Aquaporin 3 (Gill Blood Group) (AQP3))

Bindungsspezifität: C-Term

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AQP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Fluorescence Microscopy (FM)

Hersteller Produkt- Nr.: 600-401-e91

Hersteller: Rockland

Verwendungszweck: Aquaporin 3 Antibody

Kreuzreaktivität (Details): A BLAST analysis was used to suggest cross-reactivity with Aquaporin 3 from Human, Mouse, and Rat based on 100 % homology with the immunizing sequence.

Aufreinigung: Anti-Aquaporin 3 Antibody was purified by affinity chromatography.

Sterilität: Sterile filtered

Immunogen: Aquaporin 3 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to the C-terminal region of rat aquaporin 3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IF_Microscopy_Dilution: 1:200-400

Western_Blot_Dilution: 1:1000-4000

Kommentare:

Suggested Applications: IF
Anti-Aquaporin 3 Antibody is suitable for use in WB and IF microscopy. Expect a band approximately ~31.5kDa on specific lysates. May detect larger glycosylated bands ~35-50kDa. Specific conditions for reactivity should be optimized by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Preservative: 0.09 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Referenzen für anti-AQP3 Antikörper (ABIN6656926)

Posfai, Maher, Roesch, Vantaux, Sylvester, Péneau, Popovici, Kyle, Witkowski, Derbyshire: "Plasmodium vivax Liver and Blood Stages Recruit the Druggable Host Membrane Channel Aquaporin-3." in: Cell chemical biology, Vol. 27, Issue 6, pp. 719-727.e5, (2021) (PubMed).

Details zu AQP3

Target: AQP3 (Aquaporin 3 (Gill Blood Group) (AQP3))

Andere Bezeichnung: Aquaporin 3 (AQP3 Produkte)

Hintergrund:

Synonyms: AQP3, Aquaporin 3 (GIL blood group), GIL, 31.4 kDa water channel protein, Aquaglyceroporin-3

Background: Aquaporins selectively conduct water molecules in and out of the cell, while preventing the passage of ions and other solutes. Known as water channels, they are integral membrane pore proteins. Aquaporin 3 is found in the basolateral cell membrane of principal collecting duct cells and provide a pathway for water to exit these cells. AQP3 gene expression is not regulated by vasopressin.

Gene Name: Aqp3

Gen-ID: 65133

NCBI Accession: NP_113891

UniProt: P47862