Syntaxin Antikörper

Produktnummer ABIN6657443

Produktdetails anti-Syntaxin Antikörper

Target: Syntaxin

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Syntaxin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Kreuzreaktivität: Hamster, Human, Schwein, Ratte (Rattus)

Kreuzreaktivität (Details): Cross reactivity with syntaxin from other species has not been determined.

Aufreinigung: Anti-Syntaxin Monoclonal Antibody is directed against Syntaxin. Syntaxin antibody was purified by Protein G chromatography. Reactivity is expected from rat, pig and hamster.

Immunogen:

Immunogen: Anti-Syntaxin Monoclonal Antibody was produced in mouse by repeated immunizations with Synaptic immunoprecipitate (crude) from human brain.

Immunogen Type: Native Protein

Klon: SP8

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry Dilution: 1:100

Application Note: Anti-Syntaxin antibody is suitable for use in Western Blotting and IHC. Expect a band or approximately 36 kDa in size corresponding to syntaxin proteins in Western blot of rat brain lysate. Tested for use in immunohistochemistry on formalin fixed, vibratome sections. Does not work on paraffin sections. Researchers should determine optimal titers for applications that are not stated below.

Western Blot Dilution: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Details zu Syntaxin

Target: Syntaxin

Abstract: Syntaxin Produkte

Synonyme: CG11278 antikoerper, Dm Syx13 antikoerper, DmSyx13 antikoerper, Dmel\\CG11278 antikoerper, SYN13 antikoerper, Syx antikoerper, ff16 antikoerper, ff16 (69D1-70A2) antikoerper, l(3)01470 antikoerper, syx13 antikoerper, Tb03.5L5.810 antikoerper, Syntaxin 13 antikoerper, SYntaXin antikoerper, syntaxin antikoerper, Syx13 antikoerper, syx-7 antikoerper, Tc00.1047053508955.10 antikoerper, Tb927.3.5570 antikoerper, LOC100533375 antikoerper

Hintergrund:

Synonyms: Neuron-specific antigen HPC-1, Syntaxin-1A

Background: Syntaxin antibody detects Syntaxin-1A protein which is part of a family of proteins involved in the docking of synaptic vesicles with the plasma membrane. Syntaxin, along with synaptobrevin and SNAP-25, forms the SNARE complex which mediates synaptic vesicle fusion and exocytosis. Binding of Munc18-1 to the N-terminus of syntaxin 1 has been demonstrated to be essential for exocytic membrane fusion. Decreased levels of phosphorylated syntaxin 1 in the prefrontal cortex have recently been correlated with schizophrenia. Anti-Syntaxin Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

Gene Name: STX1A

Gen-ID: 6804

UniProt: Q16623

Pathways: Synaptic Vesicle Exocytosis