Calcineurin alpha Antikörper

Produktnummer ABIN6657479

Produktdetails anti-Calcineurin alpha Antikörper

Target: Calcineurin alpha

Reaktivität: Human, Ratte, Rind (Kuh)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Calcineurin alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Kreuzreaktivität: Rind (Kuh), Human, Ratte (Rattus)

Kreuzreaktivität (Details): Cross reactivity with Calcineurin alpha from other sources has not been determined.

Aufreinigung: Anti-Calcineurin alpha antibody was purified from mouse ascites by protein A chromatography.  This product reacts with human, rat, and bovine.

Immunogen:

Immunogen: Calcineurin alpha antibody was produced in mice by repeated immunizations with bovine brain calcineurin.

Immunogen Type: Other

Klon: CC-6

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry Dilution: 1:100-1:500

Application Note: Anti-Calcineurin alpha is useful for Immunohistochemistry -P and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~19.3 kDa corresponding to the appropriate cell lysate or extract.

ELISA Dilution: 1:5000

Western Blot Dilution: 0.25-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 1.2 % sodium acetate

Stabilizer: 2 mg BSA

0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: RT,4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Details zu Calcineurin alpha

Target: Calcineurin alpha

Abstract: Calcineurin alpha Produkte

Synonyme: PPP3CC antikoerper, protein phosphatase 3 catalytic subunit alpha antikoerper, PPP3CA antikoerper

Hintergrund:

Synonyms: CNA2, CNB, CNB1, CALNB1, Protein phosphatase 2B regulatory subunit 1, Protein phosphatase 3 regulatory subunit B alpha isoform 1

Background: Calcineurin, the Ca(2+)/calmodulin-regulated protein phosphatase, first detected in skeletal muscle and brain, has been found in all cells from yeast to mammals. Calcineurin A alpha (PPP3CA),is located on human chromosomes 4, Chromosomal mapping of the human genes for the calmodulin-dependent protein phosphatase (calcineurin) catalytic subunit. Calcineurin regulates bone formation by the osteoblast. This antibody is suitable for researchers interested in apoptosis, transcription factors, nuclear receptors, cancer research, Immune Response, cardiovascular disease, MAK Kinase Signaling, and AKT Signaling.

Gene Name: PPP3R1

Gen-ID: 5534

NCBI Accession: NP_000936

UniProt: P63098