SETD1A Antikörper (Internal Region, N-Term)

Produktnummer ABIN6657812

Hersteller Produkt- Nr.: 100-401-v94

Produktdetails anti-SETD1A Antikörper

Target: SETD1A (SET Domain Containing 1A (SETD1A))

Bindungsspezifität: Internal Region, N-Term

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SETD1A Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Hersteller Produkt- Nr.: 100-401-v94

Hersteller: Rockland

Verwendungszweck: Setd1a Antibody

Kreuzreaktivität (Details): Cross reactivity with Setd1a from other species not tested.

Aufreinigung: Anti-Setd1a Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.

Sterilität: Sterile filtered

Immunogen: Anti-Setd1a Antibody was produced in rabbits by repeated immunizations with three different synthetic peptides of mouse Setd1a: two containing an amino acid sequence from the N-terminal region of the protein and one containing an amino acid sequence from the internal region of the protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

ELISA_Dilution: 1:100

Western_Blot_Dilution: 1:500

Kommentare:

Anti-Setd1a Antibody has been tested by ELISA and Western Blots. Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 186 kDa in the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: None

Stabilizer: None

Preservative: 0.05 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu SETD1A

Target: SETD1A (SET Domain Containing 1A (SETD1A))

Andere Bezeichnung: Setd1a (SETD1A Produkte)

Hintergrund:

Synonyms: Histone-lysine N-methyltransferase SETD1A, Lysine N-methyltransferase 2F, SET domain-containing protein 1A, hSET1A, Set1/Ash2 histone methyltransferase complex subunit SET1

Background: SETD1A is a component of the SET1 histone methyltransferase (HMT) complex. This complex specifically methylates lysine 4 of histone H3, but only if the neighboring lysine 9 residue is not yet methylated. Methylation of H3K4 represents a specific tag for epigenetic transcriptional activation. SETD1A shows a non-overlapping localization with SETD1B, suggesting that both proteins play a specific role in the epigenetic control of chromatin structure and gene expression. Anti-Setd1a Antibody is ideal for research in Epigenetics and Gene Expression.

Gene Name: SETD1A

Gen-ID: 9739

NCBI Accession: NP_055527

UniProt: E9PYH6