ASCL2 Antikörper (C-Term)

Produktnummer ABIN6657882

Produktdetails anti-ASCL2 Antikörper

Target: ASCL2 (Achaete-Scute Complex Homolog 2 (ASCL2))

Bindungsspezifität: C-Term

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ASCL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Fluorescence Microscopy (FM)

Kreuzreaktivität (Details): Cross reactivity with Ash2 from other species not tested.

Aufreinigung: Anti-Ash2 Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.

Immunogen:

Immunogen: Anti-Ash2 Antibody was produced in rabbits by repeated immunizations with three different synthetic peptides of mouse Ash2: two containing an amino acid sequence from the internal and one containing an amino acid sequence from the C-terminal part of the protein.

Immunogen Type: Peptide

Anwendungsinformationen

Applikationshinweise:

Application Note: Anti-Ash2 Antibody is suitable for ELISA, Immunofluorescence and Western Blots. Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 68 kDa in the appropriate cell lysate or extract.

ELISA Dilution: 1:100 - 1:500

Western Blot Dilution: 1:1,000

IF Microscopy Dilution: 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

0.01 % (w/v) Sodium Azide

Stabilizer: None

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: RT,4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Details zu ASCL2

Target: ASCL2 (Achaete-Scute Complex Homolog 2 (ASCL2))

Andere Bezeichnung: Ash2 (ASCL2 Produkte)

Synonyme: ASH2 antikoerper, HASH2 antikoerper, MASH2 antikoerper, bHLHa45 antikoerper, ASCL2 antikoerper, 2410083I15Rik antikoerper, Mash2 antikoerper, achaete-scute family bHLH transcription factor 2 antikoerper, ASCL2 antikoerper, Ascl2 antikoerper

Hintergrund:

Synonyms: Set1/Ash2 histone methyltransferase complex subunit ASH2, ASH2-like protein, ASH2L1, ASH2L2, Bre2

Background: Ash2 is a component of the Set1/Ash2 histone methyltransferase (HMT) complex. This complex specifically methylates K4 of histone H3, thereby activating transcription. Methylation of K4 is blocked by premethylation of the neighboring K9, a repressor of transcription. This indicates that the Set1/Ash2 HMT complex mediates the crosstalk between K9 methylation and K4 methylation. Ash2 plays a role in hematopoiesis and may be associated with some kinds of leukemia. Anti-Ash2 Antibody is ideal for research in Gene Expression, Epigenetics, Cell Signaling and Cancer.

Gene Name: ASH2L

Gen-ID: 9070

NCBI Accession: NP_001098684

UniProt: Q9UBL3

Pathways: Stem Cell Maintenance