CD207 Antikörper

Produktnummer ABIN6657890

Produktdetails anti-CD207 Antikörper

Target: CD207 (CD207 Molecule, Langerin (CD207))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD207 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Aufreinigung: Anti-Langerin Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-Langerin from mouse based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-Langerin from other sources has not been determined.

Immunogen:

Immunogen: Langerin Antibody was produced from whole rabbit serum prepared by repeated immunizations with mouse Langerin protein at an internal amino acid sequence.

Immunogen Type: Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry Dilution: 5 μg/mL (paraffin)

Application Note: Anti-Langerin Antibody is suitable for use in CM, IHC (frozen) and WB. Expect a band approximately 36 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Western Blot Dilution: 1-3 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.20.02 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: RT,4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Details zu CD207

Target: CD207 (CD207 Molecule, Langerin (CD207))

Andere Bezeichnung: Langerin (CD207 Produkte)

Synonyme: CD207 antikoerper, CLEC4K antikoerper, RGD1565913 antikoerper, CD207 molecule antikoerper, CD207 antigen antikoerper, CD207 antikoerper, Cd207 antikoerper

Hintergrund:

Synonyms: Clec4k, C-type lectin domain family 4 member K, Langerin, CD207

Background: Anti-Langerin Antibody detects mouse Langerin. Langerin (CD207) is a type II membrane-associated C-type lectin known to be expressed exclusively by Langerhans cells. Langerin (CD207) recognizes mannose residues via its single carbohydrate recognition domain (CRD). Langerin (CD207) is localized not only on the cell surface, but also intracellularly in close association with Birbeck granules. Transfection of Langerin cDNA into fibroblasts creates a compact network of membrane structures with typical features of Birbeck granules (BG). Langerin (CD207) is thus a potent inducer of membrane superimposition and zippering leading to BG formation. Anti-Langerin Antibody is ideal for investigators involved in Toll Like Receptors, signaling, and extracelluar matrix research.

Gene Name: Cd207

Gen-ID: 246278

NCBI Accession: NP_659192

UniProt: Q8VBX4