CD4 Antikörper (PE)

Produktnummer ABIN6657902

Hersteller Produkt- Nr.: 200-508-m70

Produktdetails anti-CD4 Antikörper (PE)

Target: CD4

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD4 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS), Fluorescence Microscopy (FM)

Hersteller Produkt- Nr.: 200-508-m70

Hersteller: Rockland

Verwendungszweck: CD4 Phycoerythrin Antibody

Kreuzreaktivität (Details): Reactivity is observed against mouse CD4.

Aufreinigung: Phycoerythrin conjugated CD4 Monoclonal Antibody was Protein G Purified and is directed against mouse CD4.

Sterilität: Sterile filtered

Immunogen: Anti-CD4 Antibody (Monoclonal) was produced by repeated immunizations with Mouse CTL clone V4.

Klon: GK1-5

Isotyp: IgG2b kappa

Labeling Ratio: 1-2

Anwendungsinformationen

Applikationshinweise:

Flow_Cytometry_Dilution: 0.1-1 μg/10^6 cells

IF_Microscopy_Dilution: User Optimized

Kommentare:

Anti-CD4 is tested for Flow Cytometry (Cell Surface) and useful for Immunofluorescence. Researchers should determine optimal titers for applications that are not stated.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 0.05 % BSA

Preservative: 0.09 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.

Haltbarkeit: 6 months

Details zu CD4

Target: CD4

Andere Bezeichnung: CD4 (CD4 Produkte)

Hintergrund:

Synonyms: T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3, CD4 Antibody, L3T4, T4

Background: CD4 (cluster of differentiation 4) is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. It is a member of the immunoglobulin superfamily. On T cells, it is the co-receptor for the T cell receptor (TCR) and amplifies the signal generated by the TCR by recruiting the tyrosine kinase lck that is essential for activating many molecules involved in the signaling cascade of an activated T cell. It is an important component of the immune system and is also the cellular receptor for HIV-1. It consists of a cytoplasmic tail, one transmembrane region, and four extracellular domains, D1-D4.  It maps to 12pter-p12 region of human chromosome.

Gene Name: CD4

Gen-ID: 12504

NCBI Accession: NP_038516

UniProt: P06332

Pathways: T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events