KDM5B Antikörper (Internal Region)

Produktnummer ABIN6657904

Hersteller Produkt- Nr.: 100-401-v92

Produktdetails anti-KDM5B Antikörper

Target: KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

Bindungsspezifität: Internal Region

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KDM5B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Hersteller Produkt- Nr.: 100-401-v92

Hersteller: Rockland

Verwendungszweck: Jarid1b Antibody

Kreuzreaktivität (Details): Cross reactivity with Jarid1b from other species not tested.

Aufreinigung: Anti-Jarid1b Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.

Sterilität: Sterile filtered

Immunogen: Anti-Jarid1b Antibody was produced in rabbits by repeated immunizations with a synthetic peptide containing an amino acid sequence from the internal part of mouse Jarid1b.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

ELISA_Dilution: 1:100 - 1:200

Western_Blot_Dilution: 1:500

Kommentare:

Anti-Jarid1b Antibody has been tested by ELISA and Western Blots. Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 175 kDa in the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: None

Stabilizer: None

Preservative: 0.05 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu KDM5B

Target: KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

Andere Bezeichnung: Jarid1b (KDM5B Produkte)

Hintergrund:

Synonyms: Lysine-specific demethylase 5B, Histone demethylase JARID1B, Jumonji/ARID domain-containing protein 1B, PLU-1

Background: JARID1B is a histone demethylase which specifically demethylates mono-, di, and trimethylated lysine 4 of histone H3. It acts as a transcriptional repressor for the tumor suppressor genes BRCA1 and HOXA5 and has been associated with breast cancer development. In contrast, in melanoma JARID1B itself may function as a tumor suppressor. Anti-Jarid1b Antibody is ideal for research in Epigenetics, Chromatin Remodeling and Cancer.

Gene Name: Kdm5b

Gen-ID: 10765

NCBI Accession: NP_006609

UniProt: Q80Y84

Pathways: Warburg Effekt