KCNA1 Antikörper (Extracellular Domain)
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- Target Alle KCNA1 Antikörper anzeigen
- KCNA1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1))
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Bindungsspezifität
- Extracellular Domain
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Reaktivität
- Ratte
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser KCNA1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Fluorescence Microscopy (FM)
- Kreuzreaktivität
- Maus, Ratte (Rattus)
- Aufreinigung
- Anti-Kv1.1 Extracellular Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Kv1.1 from Mouse and rat based on 100% homology with the immunizing sequence. Cross-reactivity with Kv1.1 from other sources has not been determined. Ion Channels research.
- Immunogen
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Immunogen: Kv1.1 Extracellular Antibody was produced in mice by repeated immunizations raised against a synthetic peptide at an extracellular domain of rat Kv1.1.
Immunogen Type: Peptide
- Klon
- S36-15
- Isotyp
- IgG2b
- Top Product
- Discover our top product KCNA1 Primärantikörper
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- Applikationshinweise
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Immunohistochemistry Dilution: 0.1-1.0 μg/mL
Application Note: Anti-Kv1.1 Extracellular Antibody is suitable for use in WB and IF microscopy. Expect a band approximately ~56 kDa (could be 65-85 depending on glycosylation) on specific lysates. Specific conditions for reactivity should be optimized by the end user.
Western Blot Dilution: 1 μg/mL
IF Microscopy Dilution: 1.0-10 μg/mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
- Lagerung
- RT,4 °C,-20 °C
- Informationen zur Lagerung
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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- Target
- KCNA1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1))
- Andere Bezeichnung
- Kv1.1 (KCNA1 Produkte)
- Synonyme
- AEMK antikoerper, EA1 antikoerper, HBK1 antikoerper, HUK1 antikoerper, KV1.1 antikoerper, MBK1 antikoerper, MK1 antikoerper, RBK1 antikoerper, KCNA1 antikoerper, AI840627 antikoerper, Kca1-1 antikoerper, Kv1.1 antikoerper, Mk-1 antikoerper, Shak antikoerper, mceph antikoerper, Kcna antikoerper, Kcpvd antikoerper, potassium voltage-gated channel subfamily A member 1 antikoerper, potassium voltage-gated channel, shaker-related subfamily, member 1 antikoerper, fragile site, aphidicolin type, common, fra(12)(q24) antikoerper, KCNA1 antikoerper, Kcna1 antikoerper, FRA12E antikoerper
- Hintergrund
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Synonyms: KCA1, KCNA1, MBK1, MK1, RBK1, Shak, Voltage-gated potassium channel subunit Kv1.1, Potassium voltage gated channel subfamily A member 1, RBKI, RCK1
Background: Kv1.1, also known as potassium voltage-gated channel subfamily A member 1, is a shaker related voltage potassium channel that in humans is encoded by the SCNA1 gene. It is strongly expressed in a variety of neurons in adult rodents, and it appears to be involved in regulating neuronal excitability. Specifically it plays a role in several developmental processes including proliferation, migration and cell-cell adhesion. The Isaacs syndrome is a result of an autoimmune reaction against the Kv1.1 ion channel.
Gene Name: Kcna1
- Gen-ID
- 24520
- NCBI Accession
- NP_775118
- UniProt
- P10499
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